Primary Faculty

Gregory A. Buck, Ph.D.
Microbial genomics, molecular parasitology and pathogenicity, gene expression and RNA maturation.

Guy A. Cabral, Ph.D.
Viral oncology (herpes virus); Non-A, Non-B hepatitis, the effect of environmental chemicals on virus infections, drugs of abuse and the immune system.

Jason A. Carlyon, Ph.D.
Anaplasma phagocytophilum pathogenesis - adhesion, invasion, intracelluar survival; bacterial subversion of host cell functions; host-pathogen interactions; intracellular bacterial pathogenesis.

Gail E. Christie, Ph.D.
Role of bacteriophages in microbial evolution and pathogenesis; regulation of prokaryotic gene expression; RNA polymerase structure and function.

Daniel H. Conrad, Ph.D.
Mechanism of immediate hypersensitivity, structure and function of IgE receptors.

Cynthia N. Cornelissen, Ph.D.
Pathogenic mechanisms of Neisserria gonorrhoeae.

W. Michael Holmes, Ph.D.
RNA Protein Interactions. RNA Modification, mRNA and MicroRNA Metabolism.

Hsiu-Sheng Hsu, Ph.D.
Host-parasite relationships and experimental pathology of bacterial infectious diseases.

Thomas F. Huff, Ph.D.
Immediate hypersensitivity , mast cell differentiation, the stem cell factor/c-kit complex.

Phillip B. Hylemon, Ph.D.
Steroid metabolism by intestinal anaerobic gut bacteria, regulation of cholesterol and bile acid synthesis in hepatocyte monolayer cultures.

Kimberly K. Jefferson, Ph.D.
Bacterial gene expression and adaptation. Biofilm formation in Staphylococcus aureus.

Deborah A. Lebman, Ph.D.
The role of alterations in the transforming growth factor beta signaling pathway in the development of upper digestive tract cancers.

Roger M. Loria, Ph.D.
Pathogenic and immunological responses following virus infections, particularly human enteric viruses.

Masoud H. Manjili, Ph.D.
Immunotherapy of breast cancer, tumor escape and antigen loss, myeloid-derived suppressor cell.

Francine Marciano-Cabral, Ph.D.
Pathogenic protozoa, parasite-host interactions; parasite-immunology, host resistance mechanisms in protozoan and viral infections.

Richard T. Marconi, Ph.D.
Infectious diseases and host-pathogen interactions: molecular pathogenesis of Lyme disease, replapsing fever and other arthropod borne diseases.

Kathleen L. McCoy, Ph.D.
Immunobiology of antigen presenting cells.

Anthony V. Nicola, Ph.D.
Virus-cell interactions, cellular mechanisms of herpes simplex virus entry, herpesviral envelope glycoprotein function.

Dennis E. Ohman, Ph.D. <<<< Lab Webpage>>>>
Molecular mechanisms of pathogenesis in Pseudomonas aeruginosa; capsule biosynthesis; regulation of virulence gene expression; processing and secretion of proteases; bacterial stress-response.

Ronald B. Smeltz, Ph.D.
Immunobiology of Trapanozoma cruzi (euglenoid parasite) infection, CD8+ T cell responses, cytokines, IFN-gamma.

David B.Straus, Ph.D.
Molecular mechanism of T lymphocyte activation, development and oncogenic transformation.

Shirley M. Taylor, Ph.D.
DNA methylation and control of cell differentiation, allelic inactivation of tumor suppressor genes .

John G. Tew, Ph.D.
Role of follicular dendritic cells in the immune response and the role of immune mechanisms in the pathogenesis of periodontal disease.

Huiping Zhou, Ph.D.
The cellular/molecular mechanisms of HIV protease inhibitor-associated dysregulation of lipid metabolism and atherosclerosis.

Affiliate Faculty of Microbiology & Immunology

Gordon Archer, M.D. - Internal Medicine, Infectious Diseases
The Staphylococcal genetics, virulence factors in Staphylococcus epidermidis , prosthetic valve endocarditis, molecular basis of antibiotic resistant Staphylococcus.

Suzanne Barbour, Ph.D - Biochemistry
Phospholipid metabolism/regulation, macrophage function.

Harry D. Bear, M.D. - Surgical Oncology
Tumor immunology, suppressor T cells.

Jessica Bell, Ph.D. - Biochemistry
Mechanism of ligand recognition by innate immune (Toll-like) receptors and subsequent signal transduction. Implications in adjuvant and chemotherapeutic agent development.

James C. Burns, DDS, Ph.D. - Chair of Oral Pathology
Oral virology and oral cancer.

Sumitra Deb, Ph.D. - Biochemistry and Molecular Biophysics
Molecular biology of the human tumor suppressor p53.

Swati Palit Deb, Ph.D. - Biochemistry and Molecular Biophysics
Growth regulatory mechanisms of normal cells, particularly those deregulated during oncogenesis.

Paul M. Fawcett, Ph.D. - Internal Medicine

Gordon D. Ginder, M.D. - Director, Massey Cancer Center
Regulation of genes critical to blood diseases, cancer and lymphocyte effector function by epigenetic mechanisms and interferons.

Steven Grant, M.D. - Internal Medicine, Hematology/Oncology
Tumor biology. Modulation of anti-leukemic drug action and apoptosis by signal transduction events.

Chris Kepley, PhD, MBA - Luna nanoWorks
Using endofullerences for imaging atherosclerotic plaque, brain cancers, and neurodegenerative disease. Developing empty-cage fullerene derivatives into therapies for asthma, allergy and arthritis.

Todd Kitten, Ph.D. - Oral & Craniofacial Molecular Biology
Microbiology and genomics of oral streptococci; pathogenesis of streptococcal endocarditis.

Thomas Koertge, M.D., Ph.D. - Periodontics
Immunology of periodontal disease, secretory immunology.

Geoffrey W. Krystal, M.D., Ph.D. - Internal Medicine, Hematology/Oncology
Molecular biology of oncogenes, specifically the regulation of transcription and RNA processing of the myc gene family.

Janina Lewis, Ph.D. - Oral and Craniofacial Molecular Biology

Francis L. Macrina, Ph.D. - Oral & Craniofacial Molecular Biology
Molecular mechanisms of pathogenesis in the human oral microbes viridans streptococci and anaerobic gram negative bacteria.

D.C. Ghislaine Mayer, Ph.D. - Department of Biology
Malaria  pathogenesis, molecular and cellular parasitology. Current research focus is the molecular mechanism of erythrocytes invasion of P. falciparum

Michael McVoy, Ph.D. - Pediatrics
Mechanisms of herpesvirus genome replication, genome cleavage and packaging.

Cindy L. Munro, Ph.D. - School of Nursing
Viridans streptococcal endocarditis, role of exopolysaccharides of Streptococcus mutans in dental caries and endocarditis, ventilator associated pneumonia, management of HIV.

Luiz Shozo Ozaki, Ph.D. - Bioinformatics & Bioengineering
Comparative genomics for studying pathogenicity and phylogeny of parasitic protozoa.

Lawrence F. Povirk, M.D. - Pharmacology & Toxicology
DNA damage and mutagenesis, DNA double-strand break repair and gene rearrangements in mammalian cells. Mutagenic effects of DNA-directed chemotherapeutic agents.

John J. Ryan, Ph.D. - Biology
Molecular immunology, mediators of the allergic response, role of mast cells in allergic disease, effects of the Th2 cytokines interleukin-4 and interleukin-10 on mast cell function and activity.

Harvey Schenkein, D.D.S., Ph.D. - Periodonics
Immunobiology of periodontal disease, complement and inflammatory mediators in periodontal disease.

Lawrence B. Schwartz, M.D. - Rheumatology, Allergy & Immunology
Immunology and biochemistry of mast cells, mast cell/basophil differentiation, enzyme biochemistry, immunoassay development, molecular biology, transcriptional regulation of mast cell proteins.

Kristoffer Valerie, Ph.D. - Radiation Oncology
Molecular biology of DNA repair, radiation-induced gene expression and signal transduction mechanisms and genetic approaches to modulate cellular radioresistance.

Ping Xu, Ph.D. - Oral and Craniofacial Molecular Biology
Genomics of pathogenic protozoans.

Faculty Retreat
Micro-Immuno Faculty Research Retreat - 2007

Alumni (Since 1999)